DNA Binding Motif

Accessions: ETV2_FOXI1_2_3_4 (HumanTF2 1.0), UN0514.1 (JASPAR 2024)
Names: ETV2_FOXI1, ETV2::FOXI1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 12
Consensus: rcCGGATGTTkw
Weblogo:
PSSM: P0 A C G T
01 6419 836 4836 2051 r
02 1927 8707 2548 659 c
03 507 11255 238 57 C
04 63 3 11255 15 G
05 17 20 11255 82 G
06 11255 33 3 56 A
07 3062 64 41 11255 T
08 268 6 11255 7 G
09 0 171 6 11255 T
10 961 383 2277 11255 T
11 1477 151 6548 4707 k
12 5683 1599 1393 5572 w
Type: Heterodimer
Binding TFs: FOXI1_TF2 (Fork head domain)
ETV2_TF1 (Ets-domain)
Q3KNT2 (Ets-domain)
Q3KNT2
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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