DNA Binding Motif

						

			
Accessions: HOXB2_RFX5_2_3 (HumanTF2 1.0)

			
Names: HOXB2_RFX5
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 16
Consensus: TAATkaccmtrGCAAC
Weblogo: 
PSSM: P0      A      C      G      T
01    114     21      3   1129      T
02   1129     19    182     80      A
03   1129      0     12      0      A
04     46    122     40   1129      T
05     43    144    562    567      k
06    790    163    339    149      a
07    175    544    246    164      c
08    148    584    255    142      c
09    319    358    259    194      m
10    117    254    120    638      t
11    526    163    423     17      r
12    197     21   1129     20      G
13     69   1129     29    396      C
14   1129     20     86     61      A
15   1129     35     35     22      A
16      0   1129     17     52      C
Type: Heterodimer
Binding TFs: HOXB2_TF1 (Homeobox domain)
RFX5_TF2 (RFX DNA-binding domain, Poxvirus D5 protein-like)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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