DNA Binding Motif

Accessions: TEAD4_CLOCK_2_3_4 (HumanTF2 1.0)
Names: TEAD4_CLOCK
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 20
Consensus: GGwATGykrskkrCACGTGb
Weblogo:
PSSM: P0 A C G T
01 553 43 2842 152 G
02 164 142 2842 207 G
03 1395 198 12 1447 w
04 2842 1 18 0 A
05 10 121 2 2842 T
06 44 200 2842 369 G
07 33 1469 95 1245 y
08 630 545 789 878 k
09 786 349 1175 532 r
10 563 811 1008 460 s
11 503 329 977 1033 k
12 635 596 885 725 k
13 1180 457 1116 89 r
14 265 2842 15 0 C
15 2842 15 103 63 A
16 3 2842 5 254 C
17 165 10 2842 4 G
18 3 180 10 2842 T
19 0 7 2842 169 G
20 53 806 811 1172 b
Type: Heterodimer
Binding TFs: CLOCK_TF1 / CLOCK_TF2 (Helix-loop-helix DNA-binding domain)
TEAD4_TF1 (TEA/ATTS domain family)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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