DNA Binding Motif

						

			
Accessions: FOXO1_ELK1_2_3 (HumanTF2 1.0)

			
Names: FOXO1_ELK1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 13
Consensus: tgttgcCGGAAGt
Weblogo: 
PSSM: P0      A      C      G      T
01     70     44    105    462      t
02    149     20    462    132      g
03     55     86    151    462      t
04     82    203     94    462      t
05    123      2    462    155      g
06    138    462     78    128      c
07      0    462      0     20      C
08     11     29    462     13      G
09     12      9    462     53      G
10    462     38     26     37      A
11    347     18     15     83      A
12     68     46    330     18      G
13     41     82     91    249      t
Type: Heterodimer
Binding TFs: ELK1_TF2 (Ets-domain)
ELK1_Full (Ets-domain)
FOXO1_TF1 / FOXO1_TF2 (Fork head domain)
ELK1_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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