DNA Binding Motif

Accessions: 6xwg_D (3D-footprint 20231221)
Names: Retinoic acid receptor alpha
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal Structure of the Human RXR/RAR DNA-Binding Domain Heterodimer Bound to the Human RARb2 DR5 Response Element
Length: 5
Consensus: TgaAC
01 0 0 0 96 T
02 13 13 57 13 g
03 54 16 13 13 a
04 96 0 0 0 A
05 0 96 0 0 C
Binding TFs: 6xwg_D (Zinc finger, C4 type (two domains))
Binding Sites: 6xwg_A
Publications: Osz J, McEwen AG, Bourguet M, Przybilla F, Peluso-Iltis C, Poussin-Courmontagne P, Mély Y, Cianférani S, Jeffries CM, Svergun DI, Rochel N. Structural basis for DNA recognition and allosteric control of the retinoic acid receptors RAR-RXR. Nucleic Acids Res 48:9969-9985 (2020). [Pubmed]

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