Transcription Factor
| Accessions: | 6xwg_D (3D-footprint 20231221) |
| Names: | Nuclear receptor subfamily 1 group B member 1, RAR-alpha, RARA_HUMAN, Retinoic acid receptor alpha |
| Organisms: | Homo sapiens |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Uniprot: | P10276 |
| Length: | 80 |
| Pfam Domains: | 6-74 Zinc finger, C4 type (two domains) |
| Sequence: (in bold interface residues) | 1 PRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQ 60 61 YCRLQKCFEVGMSKESVRND |
| Interface Residues: | 15, 16, 18, 19, 25, 26, 27, 28, 29, 31, 32, 33, 36, 38, 42, 57, 61, 63, 65 |
| 3D-footprint Homologues: | 6fbq_A, 7wnh_D, 6l6q_B, 3g9m_B, 1a6y_A, 1lo1_A, 4oln_B, 8cef_H, 2han_B, 1kb2_B, 2a66_A, 8hbm_B, 5krb_G, 2nll_B, 1lat_A, 2ff0_A, 1dsz_A, 4umm_E, 3cbb_A, 7xv6_B, 4iqr_B, 2han_A, 1hcq_E, 4yhx_A, 5emc_A, 7prw_B, 5cbx_B, 4tnt_B, 5cbz_E, 4hn5_B, 5e69_A, 3g6t_A, 1r4i_A |
| Binding Motifs: | 6xwg_CD GTTCAnnnnnaGTTcA 6xwg_D TgaAC |
| Binding Sites: | 6xwg_A 6xwg_B |
| Publications: | Osz J, McEwen AG, Bourguet M, Przybilla F, Peluso-Iltis C, Poussin-Courmontagne P, Mély Y, Cianférani S, Jeffries CM, Svergun DI, Rochel N. Structural basis for DNA recognition and allosteric control of the retinoic acid receptors RAR-RXR. Nucleic Acids Res 48:9969-9985 (2020). [Pubmed] |
| Related annotations: | PaperBLAST |
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