DNA Binding Motif

Accessions: HOXB2_ELF1_2 (HumanTF2 1.0)
Names: HOXB2_ELF1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 22
Consensus: ggymATtArsrwksmGGAAGtr
Weblogo:
PSSM: P0 A C G T
01 692 804 1218 770 g
02 577 768 1618 522 g
03 727 1541 774 1943 y
04 1756 1728 713 272 m
05 3484 255 892 132 A
06 0 0 0 3484 T
07 343 1229 76 3484 t
08 3484 75 146 349 A
09 942 723 1363 455 r
10 501 970 1336 677 s
11 1339 471 934 740 r
12 1425 315 821 923 w
13 824 810 902 948 k
14 810 1235 1260 180 s
15 1106 2203 160 15 m
16 18 0 3484 18 G
17 22 0 3484 17 G
18 3484 44 15 23 A
19 3484 27 0 260 A
20 540 428 3484 36 G
21 437 769 547 1731 t
22 1017 483 1456 529 r
Type: Heterodimer
Binding TFs: ELF1_TF2 (Ets-domain, Transcription factor protein N terminal)
HOXB2_TF1 (Homeobox domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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