DNA Binding Motif

						

			
Accessions: FLI1_FOXI1_2_3_4 (HumanTF2 1.0)

			
Names: FLI1_FOXI1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 14
Consensus: TGTtkmCGGAwrtg
Weblogo: 
PSSM: P0      A      C      G      T
01    466    235    262   2118      T
02    735     70   2118    128      G
03    140    384    187   2118      T
04    400    133    646   2118      t
05    192     23    764   1354      k
06   1383    735    161     63      m
07     50   2118     34     19      C
08      4     25   2118     38      G
09     64     27   2118    173      G
10   2118    141    151    322      A
11   1417     43     60    700      w
12    681    138   1436    258      r
13    172    375    246   1325      t
14    393    383    816    525      g
Type: Heterodimer
Binding TFs: FLI1_TF2 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
FLI1_Full (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
FOXI1_TF2 (Fork head domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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