DNA Binding Motif

						

			
Accessions: FLI1_DLX2_2_3 (HumanTF2 1.0)

			
Names: FLI1_DLX2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: HT-SELEX; PWM is from validation experiment performed with full-length TFs and is not included into the dendrograms
Length: 18
Consensus: ACCGGAArTgrsyAATTA
Weblogo: 
PSSM: P0      A      C      G      T
01   2733     23    198     78      A
02     29   2932     55      5      C
03     39   2962      0      0      C
04      1      0   2984      6      G
05      1      0   2982      2      G
06   2983      7      0      0      A
07   2923      4      0     76      A
08   1345      3   1636      1      r
09     24    190     47   2796      T
10    667    434   1688    194      g
11   1119    448   1353     63      r
12    353   1130   1271    229      s
13     21   1600     42   1366      y
14   2855    119    114     30      A
15   2966    614    158    334      A
16      8     68     22   2977      T
17     31      7      2   2979      T
18   2945    945     34    302      A
Type: Heterodimer
Binding TFs: DLX2_TF2 (Homeobox domain, Homeobox protein distal-less-like N terminal )
FLI1_TF2 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
FLI1_Full (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
DLX2_Full (Homeobox domain, Homeobox protein distal-less-like N terminal )
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.