DNA Binding Motif

						

			
Accessions: TEAD4_SOX15_2 (HumanTF2 1.0)

			
Names: TEAD4_SOX15
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 18
Consensus: rACAAtrsrrhgGaATgy
Weblogo: 
PSSM: P0      A      C      G      T
01     98     22     80     36      r
02    237     28      4     64      A
03      0    237     22     15      C
04    237     17     39      0      A
05    237     10      0      2      A
06     88      7     37    237      t
07     88     19    148     49      r
08     40     75    103     19      s
09    103     44     61     29      r
10     94     47     61     34      r
11     88     61     21     67      h
12     49      5    131     52      g
13      0     31    237     31      G
14    237     61     14     51      a
15    237      7      0     27      A
16      4      5      9    237      T
17     12     30    237     70      g
18     41    118      9    119      y
Type: Heterodimer
Binding TFs: SOX15_TF2 (HMG (high mobility group) box, Domain of unknown function (DUF1898))
TEAD4_TF1 (TEA/ATTS domain family)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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