DNA Binding Motif

						

			
Accessions: HOXB2_TCF3_2 (HumanTF2 1.0)

			
Names: HOXB2_TCF3
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 17
Consensus: rCAssTGyrrsymATTA
Weblogo: 
PSSM: P0      A      C      G      T
01    392    305    677     60      r
02     37   1435     25      0      C
03   1435      0     19      0      A
04      0    797   1435      0      s
05    104    646   1435      9      s
06     14      0     11   1435      T
07      0     13   1435      6      G
08    150    522    316    447      y
09    541    179    413    303      r
10    400    270    413    353      r
11    218    441    483    293      s
12    207    443    269    516      y
13    510    925    375    166      m
14   1435     65    424     61      A
15     23      0     36   1435      T
16     71    197    112   1435      T
17   1435     62    111    216      A
Type: Heterodimer
Binding TFs: HOXB2_TF1 (Homeobox domain)
TCF3_TF2 (Helix-loop-helix DNA-binding domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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