DNA Binding Motif

						

			
Accessions: 3u2b_C (3D-footprint 20231221)

			
Names: Transcription factor SOX-4
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Structure of the Sox4 HMG domain bound to DNA
Length: 7
Consensus: cTaTTGT
Weblogo: 
PSSM: P0      A      C      G      T
01     10     64     12     10      c
02      0     12     10     74      T
03     64     12     10     10      a
04      0      0      0     96      T
05      0      0      0     96      T
06      0      0     96      0      G
07      0      0      0     96      T
Binding TFs: 3u2b_C (HMG (high mobility group) box, Domain of unknown function (DUF1898))
Binding Sites: 3u2b_A
3u2b_B
			
Publications: Jauch R, Ng C.K, Narasimhan K, Kolatkar P.R. The crystal structure of the Sox4 HMG domain-DNA complex suggests a mechanism for positional interdependence in DNA recognition. The Biochemical journal 443:39-47 (2012). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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