DNA Binding Motif

Accessions: GCM2_FOXI1_2 (HumanTF2 1.0)
Names: GCM2_FOXI1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 13
Consensus: TrTTkATrcGGGy
Weblogo:
PSSM: P0 A C G T
01 475 403 400 3244 T
02 1433 210 3244 337 r
03 472 141 367 3244 T
04 635 317 526 3244 T
05 129 46 1867 1377 k
06 3244 441 547 233 A
07 18 308 18 3244 T
08 975 277 2269 13 r
09 428 3244 1210 757 c
10 468 22 3244 213 G
11 0 38 3244 12 G
12 57 0 3244 27 G
13 546 1109 267 1323 y
Type: Heterodimer
Binding TFs: FOXI1_TF2 (Fork head domain)
GCM2_TF1 (GCM motif protein)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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