DNA Binding Motif

						

			
Accessions: GCM1_SPDEF_1 (HumanTF2 1.0)

			
Names: GCM1_SPDEF
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 23
Consensus: rTrsgGGCGGAtgyrywTCCGgs
Weblogo: 
PSSM: P0      A      C      G      T
01    210     85    375     10      r
02     28     58    119    561      T
03    174     73    415     28      r
04    169    337    220     81      s
05     65     21    456    139      g
06     35     12    616     18      G
07     25     41    613      0      G
08     91    602     15     22      C
09     19      2    618      0      G
10     13      3    623      4      G
11    617      0     63     64      A
12    149     86     36    347      t
13     93     88    352     83      g
14     58    229     88    242      y
15    285     72    201     60      r
16     52    236    130    199      y
17    363     19    259    409      w
18     50     34     26    625      T
19     17    615     57    111      C
20     30    609     50     25      C
21      2     16    467    133      G
22     20    107    372    118      g
23     98    162    228    130      s
Type: Heterodimer
Binding TFs: GCM1_TF1 (GCM motif protein)
SPDEF_TF2 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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