DNA Binding Motif

						

			
Accessions: GCM2_HES7 (HumanTF2 1.0)

			
Names: GCM2_HES7
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 20
Consensus: rTrckGGyryggCACGyGyc
Weblogo: 
PSSM: P0      A      C      G      T
01   7336   2352   4434   1995      r
02   1033   1301   1872  11770      T
03   4610   1669   7161      1      r
04   2407   4498   2743   2123      c
05   1749   1836   7158   4612      k
06     31     19  11770    177      G
07     16      0  11770     95      G
08   2164   6338   3057  11770      y
09   3639   2519   3469   2144      r
10   1391   3393   2608   4378      y
11   2213   2719   5068   1771      g
12   5113   2758  11770   1414      g
13    801  11770     43     25      C
14  11770    376   2660    810      A
15    166  11770    105    504      C
16   1339    138  11770    168      G
17   1626   4609    681   7162      y
18    389     88  11770   1786      G
19   1133   4183   1903   4551      y
20   2300   3978   2744   2749      c
Type: Heterodimer
Binding TFs: GCM2_TF1 (GCM motif protein)
HES7_TF2 (Helix-loop-helix DNA-binding domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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