DNA Binding Motif

						

			
Accessions: HOXD12_ELK3_2 (HumanTF2 1.0)

			
Names: HOXD12_ELK3
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 16
Consensus: avCGGAAGTrrTwAAr
Weblogo: 
PSSM: P0      A      C      G      T
01     85      5     28      9      a
02     47     50     63     12      v
03     32    113      1      0      C
04      0      0    113      0      G
05      0      0    113      0      G
06    113      0      0      0      A
07    113      3      2      6      A
08      4     21    113      0      G
09     11     23      3    113      T
10    113     34     84     13      r
11    113     10     77      4      r
12      0      0      0    113      T
13    113     11     21     64      w
14    113      0      4     18      A
15    113     13     22     12      A
16     29     11     63     10      r
Type: Heterodimer
Binding TFs: ELK3_TF2 (Ets-domain)
HOXD12_TF1 (Homeobox domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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