DNA Binding Motif

						

			
Accessions: TFAP2C_ELK1 (HumanTF2 1.0)

			
Names: TFAP2C_ELK1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 20
Consensus: yGCCksrGGsgrCGGAAGyg
Weblogo: 
PSSM: P0      A      C      G      T
01   3302   4487   3570   6320      y
02    890   6236  17679    608      G
03      0  17679     42      0      C
04     39  17679    178   2593      C
05   3315   7010  13653  17679      k
06   2678   5960   5783   3258      s
07   6878   1950   8160    691      r
08   2097      4  17679      0      G
09      0      0  17679     24      G
10    639   8977   8702    897      s
11   3693   1792   9536   2658      g
12   6642   3064   7434    539      r
13    874  17679    241    108      C
14      5     22  17679     14      G
15      9     54  17679     48      G
16  17679      0      0    112      A
17  17679    327     55   1515      A
18   2801   1060  17679    139      G
19   1500   5812   3662  11867      y
20   3708   1503   9405   3064      g
Type: Heterodimer
Binding TFs: ELK1_TF2 (Ets-domain)
ELK1_Full (Ets-domain)
TFAP2C_TF1 (Transcription factor AP-2)
ELK1_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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