DNA Binding Motif

						

			
Accessions: POU2F1_FOXO6_1 (HumanTF2 1.0)

			
Names: POU2F1_FOXO6
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 31
Consensus: GmATATKCAwrwswysrammmawkrwmAACA
Weblogo: 
PSSM: P0      A      C      G      T
01     66     21    582     55      G
02    417    231      0     14      m
03    648     28      9    186      A
04      4      2     19    648      T
05    648      0     10      0      A
06     20      5      4    648      T
07      0      0    469    179      K
08     16    648     35     59      C
09    482     18     12    136      A
10    252    109     67    219      w
11    272     44    233     99      r
12    351     51     71    176      w
13    130    259    167     92      s
14    211    101     58    278      w
15     65    254     92    238      y
16    114    248    194     92      s
17    268     65    172    144      r
18    353    155     49     92      a
19    173    273     57    145      m
20    234    195    129     90      m
21    292    163     59    133      m
22    251    113    156    127      a
23    288     43     86    231      w
24    136    126    213    173      k
25    399     67    249      9      r
26    340     79     60    308      w
27    203    445      3     19      m
28    648     10     40     34      A
29    648     53    144     47      A
30     25    648     11    223      C
31    648     26    107     75      A
Type: Heterodimer
Binding TFs: FOXO6_TF2 (Fork head domain)
POU2F1_TF1 (Homeobox domain, Pou domain - N-terminal to homeobox domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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