DNA Binding Motif

						

			
Accessions: ETV2_ONECUT2_2_3 (HumanTF2 1.0)

			
Names: ETV2_ONECUT2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 19
Consensus: rcCGGAArygryATCGATy
Weblogo: 
PSSM: P0      A      C      G      T
01   1109    182    658    304      r
02    364   1767    504     79      c
03    200   1767      9      0      C
04      8      4   1767      7      G
05      0      2   1767      0      G
06   1767      1      0     11      A
07   1767     47      6    584      A
08    580     70   1085     31      r
09     80    665    214    808      y
10    395    396    635    340      g
11    445    426    625    271      r
12    324    493    219    731      y
13   1767      3     42     86      A
14     40     12     12   1767      T
15     52   1767     31    480      C
16     11      0   1767      0      G
17   1767      0      0     11      A
18     73    432     72   1767      T
19     60    811     88    808      y
Type: Heterodimer
Binding TFs: ONECUT2_TF2 (Homeobox domain, CUT domain)
ETV2_TF1 (Ets-domain)
ONECUT2_Full (Homeobox domain, CUT domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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