DNA Binding Motif

Accessions: ELK1_TBX21_2_3_4 (HumanTF2 1.0)
Names: ELK1_TBX21
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 14
Consensus: TmaCACmGGAwvhg
Weblogo:
PSSM: P0 A C G T
01 42 98 61 611 T
02 188 239 118 67 m
03 420 13 192 151 a
04 16 611 30 51 C
05 611 28 150 5 A
06 130 611 72 5 C
07 346 611 40 11 m
08 20 12 611 11 G
09 0 0 611 7 G
10 611 13 18 57 A
11 611 186 61 393 w
12 554 536 611 313 v
13 164 170 102 175 h
14 129 149 185 149 g
Type: Heterodimer
Binding TFs: ELK1_TF2 (Ets-domain)
ELK1_Full (Ets-domain)
TBX21_TF2 (T-box)
ELK1_TF1 (Ets-domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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