DNA Binding Motif

						

			
Accessions: HOXB2_TCF3_1 (HumanTF2 1.0)

			
Names: HOXB2_TCF3
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 17
Consensus: vCACCTGcmmcymATyA
Weblogo: 
PSSM: P0      A      C      G      T
01    819    834    886    113      v
02      0   2652      0      0      C
03   2652     18      7      0      A
04      1   2652    649     73      C
05     49   2652    799     22      C
06      5     17      0   2652      T
07     12     14   2652     20      G
08    560   1238    324    530      c
09   1051    831    326    445      m
10    813    893    376    571      m
11    514   1012    650    477      c
12    479   1136    333    704      y
13    863   1789    438    191      m
14   2652    394    490     95      A
15      0     68     36   2652      T
16     97   1067    146   2652      y
17   2652     82    131    305      A
Type: Heterodimer
Binding TFs: HOXB2_TF1 (Homeobox domain)
TCF3_TF2 (Helix-loop-helix DNA-binding domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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