DNA Binding Motif

						

			
Accessions: HOXB2_PAX9_1 (HumanTF2 1.0)

			
Names: HOXB2_PAX9
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 21
Consensus: cccaTTaGTCACGCwTsRsTk
Weblogo: 
PSSM: P0      A      C      G      T
01     97    171    101     75      c
02     55    208     78    103      c
03    148    230    142    107      c
04    422     19    139     49      a
05     19     48     14    441      T
06     15    133     21    405      T
07    423    148     83     76      a
08      0      0    443      3      G
09     25      0      7    431      T
10      0    434      0     21      C
11    440      8      0      0      A
12      0    418      0     50      C
13      0      0    443      0      G
14      0    409     67      0      C
15    256     28     10    176      w
16      4     75      0    437      T
17      0    182    261      4      s
18    317      0    126      0      R
19     66    168    118     91      s
20      3    108      8    435      T
21     34      3    338    178      k
Type: Heterodimer
Binding TFs: HOXB2_TF1 (Homeobox domain)
PAX9_TF2 ('Paired box' domain, Homeodomain-like domain)
PAX9_TF1 ('Paired box' domain, Homeodomain-like domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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