DNA Binding Motif

Accessions: POU2F1_ELK1_1 (HumanTF2 1.0)
Names: POU2F1_ELK1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 13
Consensus: aCCGGAwATGCAw
Weblogo:
PSSM: P0 A C G T
01 179 44 4 48 a
02 34 275 21 3 C
03 4 275 8 11 C
04 6 1 275 2 G
05 48 54 275 15 G
06 275 3 18 2 A
07 155 2 3 275 w
08 275 2 7 1 A
09 8 10 7 275 T
10 8 4 275 41 G
11 27 275 30 43 C
12 275 62 5 34 A
13 110 8 55 102 w
Type: Heterodimer
Binding TFs: ELK1_TF2 (Ets-domain)
ELK1_Full (Ets-domain)
POU2F1_TF1 (Homeobox domain, Pou domain - N-terminal to homeobox domain)
ELK1_TF1 (Ets-domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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