DNA Binding Motif

						

			
Accessions: 4mte_ABCD (3D-footprint 20231221)

			
Names: Zinc uptake regulation protein
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Zinc Uptake Regulator Complexed with Zinc and DNA
Length: 20
Consensus: TGAnATGnTATAATATCACA
Weblogo: 
PSSM: P0      A      C      G      T
01      3      3      3     87      T
02      0      0     96      0      G
03     81      6      3      6      A
04     24     24     24     24      n
05     82      3      5      6      A
06      0      0      0     96      T
07      0      0     96      0      G
08     24     24     24     24      n
09      0      0      0     96      T
10     96      0      0      0      A
11      0      0      0     96      T
12     96      0      0      0      A
13     74      6     10      6      A
14      0     17      0     79      T
15     96      0      0      0      A
16      6      6      6     78      T
17      6     68     12     10      C
18     96      0      0      0      A
19      0     96      0      0      C
20     96      0      0      0      A
Type: Heterodimer
Binding TFs: 4mte_A (Ferric uptake regulator family)
4mte_B (Ferric uptake regulator family)
4mte_C (Ferric uptake regulator family)
4mte_D (Ferric uptake regulator family)
Binding Sites: 4mte_Y
4mte_Z
			
Publications: Gilston B.A, Wang S, Marcus M.D, Canalizo-Hernández M.A, Swindell E.P, Xue Y, Mondragón A, O'Halloran T.V. Structural and mechanistic basis of zinc regulation across the E. coli Zur regulon. PLoS biology 12:e1001987 (2014). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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