Transcription Factor

Accessions: 4mtd_D (3D-footprint 20231221), 4mte_D (3D-footprint 20231221)
Names: Zinc uptake regulation protein, Zinc uptake regulator, ZUR_ECOLI
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P0AC51
Length: 151
Pfam Domains: 19-137 Ferric uptake regulator family
Sequence:
(in bold interface residues)
1 EKTTTQELLAQAEKICAQRNVRLTPQRLEVLRLMSLQDGAISAYDLLDLLREAEPQAKPP 60
61 TVYRALDFLLEQGFVHKVESTNSYVLCHLFDQPTHTSAMFICDRCGAVKEECAEGVEDIM 120
121 HTLAAKMGFALRHNVIEAHGLCAACVEVEAC
Interface Residues: 22, 44, 58, 59, 60, 61, 63, 64
3D-footprint Homologues: 7vpz_N, 7vo0_N, 7x74_H, 4mtd_D
Binding Motifs: 4mtd_ABCD TGAaATGTTATAAyATnACA
4mte_ABCD TGAnATGnTATAATATCACA
4mte_D TATcACA
Binding Sites: 4mtd_Y / 4mte_Y
4mtd_Z / 4mte_Z
Publications: Gilston B.A, Wang S, Marcus M.D, Canalizo-Hernández M.A, Swindell E.P, Xue Y, Mondragón A, O'Halloran T.V. Structural and mechanistic basis of zinc regulation across the E. coli Zur regulon. PLoS biology 12:e1001987 (2014). [Pubmed]
Related annotations: PaperBLAST

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