DNA Binding Motif

						

			
Accessions: 2hdd_AB (3D-footprint 20231221)

			
Names: PROTEIN (ENGRAILED HOMEODOMAIN Q50K)
Organisms: Drosophila melanogaster
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: ENGRAILED HOMEODOMAIN Q50K VARIANT DNA COMPLEX
Length: 12
Consensus: TCcnnGGaTTAC
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0      0     96      T
02      0     96      0      0      C
03     14     54     14     14      c
04     24     24     24     24      n
05     24     24     24     24      n
06      0      0     96      0      G
07      0      0     96      0      G
08     51     17     14     14      a
09      0      0      0     96      T
10      0      0      0     96      T
11     96      0      0      0      A
12     16     66      7      7      C
Type: Heterodimer
Binding TFs: 2hdd_A (Homeobox domain)
2hdd_B (Homeobox domain)
Binding Sites: 2hdd_C
2hdd_D
			
Publications: Tucker-Kellogg L, Rould M.A, Chambers K.A, Ades S.E, Sauer R.T, Pabo C.O. Engrailed (Gln50-->Lys) homeodomain-DNA complex at 1.9 A resolution: structural basis for enhanced affinity and altered specificity. Structure (London, England : 1993) 5:1047-54 (1997). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.