DNA Binding Motif

						

			
Accessions: ETV2_DLX3_2_3 (HumanTF2 1.0)

			
Names: ETV2_DLX3
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 18
Consensus: rcCGGAAryrrgyaATTa
Weblogo: 
PSSM: P0      A      C      G      T
01   3136    659   1636    824      r
02   1567   3195   1576    483      c
03   1622   4772    140      8      C
04      0      1   4772      6      G
05      4      0   4772      7      G
06   4772      0      0     24      A
07   4772    312     23   1435      A
08   1824    511   2354     83      r
09    706   1508    579   1978      y
10   1373   1023   1458    917      r
11   1472   1163   1528    608      r
12    942   1113   2008    709      g
13    680   2757    302   2015      y
14   4772   2066   1373   1284      a
15   4772   1211    612    406      A
16    175    108    125   4772      T
17    297   1226    464   4772      T
18   4772    218   1612   1005      a
Type: Heterodimer
Binding TFs: DLX3_TF2 (Homeobox domain)
DLX3_Crystal (Homeobox domain)
DLX3_Full (Homeobox domain, Homeobox protein distal-less-like N terminal )
ETV2_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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