DNA Binding Motif

Accessions: TEAD4_EOMES_2_3_4_5 (HumanTF2 1.0)
Names: TEAD4_EOMES
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 16
Consensus: GGwATGyragGTGygr
Weblogo:
PSSM: P0 A C G T
01 50 0 401 58 G
02 5 20 401 28 G
03 280 34 20 122 w
04 401 6 19 14 A
05 0 19 24 401 T
06 3 27 401 29 G
07 7 179 38 177 y
08 148 38 253 48 r
09 401 118 168 89 a
10 63 132 401 96 g
11 5 13 401 16 G
12 7 55 14 401 T
13 7 6 401 22 G
14 61 108 39 193 y
15 42 91 197 72 g
16 264 44 138 43 r
Type: Heterodimer
Binding TFs: EOMES_TF2 (T-box)
TEAD4_TF1 (TEA/ATTS domain family)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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