DNA Binding Motif

Accessions: HOXB2_ELF1_2_3_4 (HumanTF2 1.0)
Names: HOXB2_ELF1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 17
Consensus: TaATkrwyvMGGAAGtr
Weblogo:
PSSM: P0 A C G T
01 169 40 31 1262 T
02 1262 107 390 302 a
03 1262 65 236 32 A
04 33 329 232 1262 T
05 72 167 837 426 k
06 833 99 429 167 r
07 338 309 218 397 w
08 286 332 251 394 y
09 361 349 486 66 v
10 330 873 53 6 M
11 0 9 1262 4 G
12 0 0 1262 1 G
13 1262 24 0 22 A
14 1262 31 1 146 A
15 141 96 1262 2 G
16 311 548 340 1262 t
17 375 260 475 152 r
Type: Heterodimer
Binding TFs: ELF1_TF2 (Ets-domain, Transcription factor protein N terminal)
HOXB2_TF1 (Homeobox domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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