DNA Binding Motif

Accessions: 5e8i_D (3D-footprint 20231221)
Names: Friend leukemia integration 1 transcription factor
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of the DNA binding domain of human transcription factor FLI1 in complex with a 10-mer DNA ACCGGAAGTG
Length: 6
Consensus: CGGAAG
Weblogo:
PSSM: P0 A C G T
01 9 67 9 11 C
02 0 0 96 0 G
03 0 0 96 0 G
04 96 0 0 0 A
05 67 9 11 9 A
06 11 9 67 9 G
Binding TFs: 5e8i_D (Ets-domain)
Binding Sites: 5e8i_E
5e8i_F
Publications: Hou C, Tsodikov OV. Structural Basis for Dimerization and DNA Binding of Transcription Factor FLI1. Biochemistry 54:7365-74 (2015). [Pubmed]

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