DNA Binding Motif

						

			
Accessions: ETV2_DLX3_2_3_4 (HumanTF2 1.0)

			
Names: ETV2_DLX3
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 18
Consensus: TAATkrswacCGGAWryr
Weblogo: 
PSSM: P0      A      C      G      T
01    411    346    144   2071      T
02   2071    122    309    121      A
03   2071     28     38     40      A
04     92    215    636   2071      T
05    488    608   1505   2071      k
06    765    333   1307    322      r
07    455    615    786    216      s
08    953    233    306    579      w
09   1226    125    213    507      a
10    513    809    382    367      c
11    300   2071     32      0      C
12      7      5   2071      8      G
13      0      7   2071     27      G
14   2071     15     22     25      A
15   2071     54      0    750      W
16    763     59   1309     21      r
17    182    785    224   1286      y
18    627    358    767    320      r
Type: Heterodimer
Binding TFs: DLX3_TF2 (Homeobox domain)
DLX3_Crystal (Homeobox domain)
DLX3_Full (Homeobox domain, Homeobox protein distal-less-like N terminal )
ETV2_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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