DNA Binding Motif

						

			
Accessions: TEAD4_DLX2_2 (HumanTF2 1.0)

			
Names: TEAD4_DLX2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 17
Consensus: rCATwCyacwryAATTA
Weblogo: 
PSSM: P0      A      C      G      T
01    121     12    109     25      r
02     64    230     24      9      C
03    230      1     20      1      A
04     14      4      2    230      T
05    136      6     35    230      w
06     22    230     24     35      C
07     20    154      4     76      y
08     79     46     48     57      a
09     56     60     56     57      c
10     81     50     39     59      w
11     60     52     74     43      r
12     51    230     15    484      y
13    230     16     16      8      A
14    230      9      0     23      A
15      5      7      0    230      T
16     14      0      6    230      T
17    230      1     19     20      A
Type: Heterodimer
Binding TFs: DLX2_TF2 (Homeobox domain, Homeobox protein distal-less-like N terminal )
TEAD4_TF1 (TEA/ATTS domain family)
DLX2_Full (Homeobox domain, Homeobox protein distal-less-like N terminal )
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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