DNA Binding Motif

						

			
Accessions: SOX6_TBX21_1 (HumanTF2 1.0)

			
Names: SOX6_TBX21
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 21
Consensus: rgGTGtkryttwdksywTTGT
Weblogo: 
PSSM: P0      A      C      G      T
01    454     32    251    168      r
02    228    157    705    186      g
03      0     57    705     46      G
04     14    141     15    705      T
05      0      6    705      3      G
06    134    164    110    705      t
07     29    167    236    274      k
08    351     57    223     75      r
09    144    206    157    198      y
10    149    134    175    248      t
11    164    134    164    244      t
12    198    115    170    222      w
13    190     93    204    219      d
14    108    126    192    279      k
15     82    249    230    143      s
16    138    389    113    317      y
17    705     25     74    302      w
18    112     23     34    705      T
19      6      7     26    705      T
20     44     20    705      2      G
21      6     10     26    705      T
Type: Heterodimer
Binding TFs: TBX21_TF2 (T-box)
SOX6_TF1 / SOX6_TF2 (HMG (high mobility group) box, Domain of unknown function (DUF1898))
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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