DNA Binding Motif

						

			
Accessions: TEAD4_HOXA2_2 (HumanTF2 1.0)

			
Names: TEAD4_HOXA2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 17
Consensus: rCATwCCrawctmATTA
Weblogo: 
PSSM: P0      A      C      G      T
01   2578     96   2011     75      r
02    611   4588    194      0      C
03   4588     46     88      0      A
04      0      0      0   4588      T
05   2983     66    271   4588      w
06     80   4588    389     57      C
07    147   3877      0    583      C
08   1750    628   1439    772      r
09   1970    968    538   1113      a
10   1431    919   1014   1224      w
11    760   2072   1046    710      c
12    670   1070    741   2108      t
13   2192   4588    910    203      m
14   4588     35   1008      0      A
15     26     34      0   4588      T
16     55    528      8   4588      T
17   4588    116     98    127      A
Type: Heterodimer
Binding TFs: HOXA2_TF2 (Homeobox domain)
TEAD4_TF1 (TEA/ATTS domain family)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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