DNA Binding Motif

						

			
Accessions: FOXO1_ELK1_1 (HumanTF2 1.0), UN0536.1 (JASPAR 2024)

			
Names: FOXO1_ELK1, FOXO1::ELK1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 13
Consensus: rsCGGAwGTTdtk
Weblogo: 
PSSM: P0      A      C      G      T
01    640    102    644    207      r
02    162    867    418    135      s
03    160   1284     64     29      C
04     19      7   1284      8      G
05     14     51   1284     38      G
06   1284     17     53     55      A
07    786     36     10   1284      w
08    136     25   1284      5      G
09     54     51     48   1284      T
10    138     96    193   1284      T
11    465     16    820    435      d
12    329    230    253   1284      t
13     76    301    481    427      k
Type: Heterodimer
Binding TFs: ELK1_TF2 (Ets-domain)
ELK1_Full (Ets-domain)
FOXO1_TF1 / FOXO1_TF2 (Fork head domain)
Q12778 (Fork head domain)
ELK1_TF1 (Ets-domain)
Q12778
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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