DNA Binding Motif

						

			
Accessions: ETV2_NHLH1_1 (HumanTF2 1.0), UN0517.1 (JASPAR 2024)

			
Names: ETV2_NHLH1, ETV2::NHLH1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 17
Consensus: mGCAGCTGCCGGAWgyw
Weblogo: 
PSSM: P0      A      C      G      T
01   2917   2203   1093    159      m
02    659    190   6371    261      G
03      2   6371      0      5      C
04   6371      3    122      0      A
05      0   1680   6371    141      G
06     20   6371    170      4      C
07      8      5      8   6371      T
08    152      5   6371     20      G
09      5   6371     36      0      C
10      0   6371      0      4      C
11      0     17   6371      2      G
12     39      5   6371      5      G
13   6371      0      0    219      A
14   4638    222      0   1734      W
15   1657     94   4715    794      g
16      5   2378      2   3994      y
17   1717   1156   1263   2235      w
Type: Heterodimer
Binding TFs: NHLH1_TF2 (Helix-loop-helix DNA-binding domain)
ETV2_TF1 (Ets-domain)
Q3KNT2 (Ets-domain)
Q3KNT2
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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