DNA Binding Motif

						

			
Accessions: ERF_HES7_2 (HumanTF2 1.0)

			
Names: ERF_HES7
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 20
Consensus: kkCACGyGCysacCGGAaGt
Weblogo: 
PSSM: P0      A      C      G      T
01     18     17     34     53      k
02     13     22     34     53      k
03      7    122      7      0      C
04    122     14     24      8      A
05      3    122      0      0      C
06      6      5    122      5      G
07     15     68      2    122      y
08      5      0    122      0      G
09      5     86     16     15      C
10     15     34     16     56      y
11     22     44     31     24      s
12     47     17     28     29      a
13     23    122     45     26      c
14     34    122      1      1      C
15      2      0    122      2      G
16      9      0    122      2      G
17    122      0     11      7      A
18    122     19     14     38      a
19     21      9     93      0      G
20     18     26      8     70      t
Type: Heterodimer
Binding TFs: HES7_TF2 (Helix-loop-helix DNA-binding domain)
ERF_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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