DNA Binding Motif

						

			
Accessions: ERF_HOXA3 (HumanTF2 1.0)

			
Names: ERF_HOXA3
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 20
Consensus: asCGGAwryrrargymaTTA
Weblogo: 
PSSM: P0      A      C      G      T
01    504     71    124     86      a
02    179    426    202      0      s
03     60    628     13      2      C
04      0      0    628      0      G
05      0      0    628      5      G
06    628      7      0      0      A
07    451     66      0    177      w
08    230     46    338     13      r
09     47    165    100    317      y
10    204    124    160    139      r
11    158    130    201    138      r
12    260    116    115    137      a
13    166    129    199    134      r
14    132    134    242    121      g
15    232    336    101    292      y
16    280    348     62     83      m
17    628    185    119     95      a
18      8     34     18    628      T
19     65     83     13    628      T
20    628     50     64    165      A
Type: Heterodimer
Binding TFs: ERF_TF1 (Ets-domain)
HOXA3_TF1 / HOXA3_TF2 (Homeobox domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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