Transcription Factor
| Accessions: | 5zk1_A (3D-footprint 20231221) |
| Names: | cAMP-responsive element-binding protein 1, CREB-1, CREB1_HUMAN, Cyclic AMP-responsive element-binding protein 1 |
| Organisms: | Homo sapiens |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Uniprot: | P16220 |
| Length: | 53 |
| Pfam Domains: | 1-52 bZIP transcription factor 3-49 Basic region leucine zipper |
| Sequence: (in bold interface residues) | 1 KREVRLMKNREAARESRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYS |
| Interface Residues: | 9, 10, 12, 13, 16, 17 |
| 3D-footprint Homologues: | 5t01_B, 5vpe_D, 1dh3_C |
| Binding Motifs: | 5zk1_AC CGtCnnc |
| Binding Sites: | 5zk1_B |
| Publications: | Song Y, Zhai L, Valencia Swain J, Chen Y, Wang P, Chen L, Liu Y, Xiang S. Structural Insights into the CRTC2-CREB Complex Assembly on CRE. J Mol Biol 430:1926-1939 (2018). [Pubmed] |
| Related annotations: | PaperBLAST |
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