Transcription Factor

						

			
Accessions: 1gt0_D (3D-footprint 20231221)

			
Names: SOX2_MOUSE, TRANSCRIPTION FACTOR SOX-2
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P48432
Length: 79
Pfam Domains:      2-63 Domain of unknown function (DUF1898)
     3-71 HMG (high mobility group) box
Sequence: 
(in bold interface residues)		   1 DRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLR   60
  61 ALHMKEHPDYKYRPRRKTK
Interface Residues: 5, 8, 10, 11, 12, 14, 18, 22, 29, 30, 31, 34, 72, 76
3D-footprint Homologues: 3tmm_A, 4y60_C, 2gzk_A, 1j5n_A, 6jrp_D, 2lef_A, 3u2b_C, 1o4x_B, 7m5w_A, 3f27_D, 4s2q_D, 1qrv_A, 1hry_A, 3tq6_B, 1ckt_A, 7zie_A
Binding Motifs: 1gt0_CD CTTTGTnnGGATGCTAAT
1gt0_D CTTTGTnng
Binding Sites: 1gt0_A
1gt0_B
			
Publications: Reményi A, Lins K, Nissen L.J, Reinbold R, Schöler H.R, Wilmanns M. Crystal structure of a POU/HMG/DNA ternary complex suggests differential assembly of Oct4 and Sox2 on two enhancers. Genes & development 17:2048-59 (2003). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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