DNA Binding Motif

						

			
Accessions: 1gt0_CD (3D-footprint 20231221)

			
Names: OCTAMER-BINDING TRANSCRIPTION FACTOR 1
Organisms: Homo sapiens, Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of a POU/HMG/DNA ternary complex
Length: 18
Consensus: CTTTGTnnGGATGCTAAT
Weblogo: 
PSSM: P0      A      C      G      T
01      0     96      0      0      C
02      0      0      0     96      T
03      0      0      0     96      T
04      0      0      0     96      T
05     13      0     82      1      G
06      0      0      0     96      T
07     24     24     24     24      n
08     24     24     24     24      n
09     13      9     68      6      G
10      6      6     78      6      G
11     96      0      0      0      A
12      0      0      0     96      T
13      0      0     96      0      G
14      0     96      0      0      C
15      0      6      0     90      T
16     75      6      9      6      A
17     96      0      0      0      A
18      6      1      0     89      T
Type: Heterodimer
Binding TFs: 1gt0_C (Homeobox domain, Pou domain - N-terminal to homeobox domain)
1gt0_D (HMG (high mobility group) box, Domain of unknown function (DUF1898))
Binding Sites: 1gt0_A
1gt0_B
			
Publications: Reményi A, Lins K, Nissen L.J, Reinbold R, Schöler H.R, Wilmanns M. Crystal structure of a POU/HMG/DNA ternary complex suggests differential assembly of Oct4 and Sox2 on two enhancers. Genes & development 17:2048-59 (2003). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.