Transcription Factor

						

			
Accessions: 1b72_A (3D-footprint 20231221)

			
Names: Homeobox protein Hox-2I, HOMEOBOX PROTEIN HOX-B1, HXB1_HUMAN
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P14653
Length: 68
Pfam Domains:     11-64 Homeobox domain
Sequence: 
(in bold interface residues)		   1 ARTFDWMKVLRTNFTTRQLTELEKEFHFNKYLSRARRVEIAATLELNETQVKIWFQNRRM   60
  61 KQKKRERE
Interface Residues: 7, 8, 11, 49, 50, 52, 53, 56, 57, 60, 61, 64
3D-footprint Homologues: 7q3o_C, 6m3d_C, 1au7_A, 5flv_I, 3l1p_A, 2ld5_A, 1fjl_B, 5zjt_E, 3a01_E, 2h1k_B, 7psx_B, 1b72_A, 5hod_A, 3lnq_A, 2lkx_A, 1puf_A, 1ig7_A, 6a8r_A, 3cmy_A, 2hdd_A, 5jlw_D, 3rkq_B, 2r5y_A, 1puf_B, 1jgg_B, 6es3_K, 4xrs_G, 3d1n_M, 2hos_A, 1nk2_P, 5zfz_A, 4cyc_A, 4j19_B, 1le8_A, 7xrc_C, 1e3o_C, 2xsd_C, 1k61_B, 1o4x_A, 8g87_X, 4qtr_D, 1mnm_C, 1du0_A, 1zq3_P
Binding Motifs: 1b72_A TTCa
1b72_AB ATGATTGAA
Binding Sites: 1b72_D
1b72_E
			
Publications: Piper D.E, Batchelor A.H, Chang C.P, Cleary M.L, Wolberger C. Structure of a HoxB1-Pbx1 heterodimer bound to DNA: role of the hexapeptide and a fourth homeodomain helix in complex formation. Cell 96:587-97 (1999). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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