Transcription Factor

Accessions: 1h89_A (3D-footprint 20231221), 1h89_B (3D-footprint 20231221)
Names: C/EBP beta, CAAT/ENHANCER BINDING PROTEIN BETA, CCAAT/enhancer-binding protein beta, CEBPB_HUMAN, LAP, LIP, Liver activator protein, Liver-enriched inhibitory protein, Nuclear factor NF-IL6, TCF-5, Transcription factor 5
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P17676
Length: 64
Pfam Domains: 1-51 Basic region leucine zipper
3-57 bZIP transcription factor
Sequence:
(in bold interface residues)
1 EYKIRRERNNIAVRKSRDKAKMRNLETQHKVLELTAENERLQKKVEQLSRELSTLRNLFK 60
61 QLPE
Interface Residues: 5, 6, 9, 10, 12, 13, 16, 17
3D-footprint Homologues: 2wt7_A, 1nwq_C, 6mg1_B, 2c9l_Z, 2dgc_A
Binding Motifs: 1h89_ABC TGGCGCAAnnnntAACGGa
1h89_A TTGCg
Binding Sites: 1h89_D
1h89_E
Publications: Tahirov T.H, Sato K, Ichikawa-Iwata E, Sasaki M, Inoue-Bungo T, Shiina M, Kimura K, Takata S, Fujikawa A, Morii H, Kumasaka T, Yamamoto M, Ishii S, Ogata K. Mechanism of c-Myb-C/EBP beta cooperation from separated sites on a promoter. Cell 108:57-70 (2002). [Pubmed]
Related annotations: PaperBLAST

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