Transcription Factor
| Accessions: | 4yg1_B (3D-footprint 20231221), 4yg1_C (3D-footprint 20231221), 4yg4_A (3D-footprint 20231221), 4yg4_C (3D-footprint 20231221), 4yg4_D (3D-footprint 20231221), 4yg7_B (3D-footprint 20231221), 4yg7_E (3D-footprint 20231221) |
| Names: | Antitoxin HipB, HIPB_ECOLI |
| Organisms: | Escherichia coli, strain K12 |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Uniprot: | P23873 |
| Length: | 69 |
| Pfam Domains: | 9-64 Helix-turn-helix domain 9-62 Helix-turn-helix domain 13-64 Helix-turn-helix domain 15-66 Helix-turn-helix 19-64 Cro/C1-type HTH DNA-binding domain |
| Sequence: (in bold interface residues) | 1 FQKIYSPTQLANAMKLVRQQNGWTQSELAKKIGIKQATISNFENNPDNTTLTTFFKILQS 60 61 LELSMTLCD |
| Interface Residues: | 25, 26, 35, 36, 37, 38, 40, 41, 44, 47, 48 |
| 3D-footprint Homologues: | 3cro_R, 3oqm_C, 1per_L, 3dnv_B, 4z5h_A, 3zkc_A, 5k98_B, 4lln_I, 5gpc_B |
| Binding Motifs: | 4yg1_ABCD TATCnnnnnnnATGnTAnnnnnnnnnnnATnCnnnnnnCGGATA 4yg1_B GATA 4yg4_ABCD ATaCnnnnnnngGGA 4yg7_BCDEGK TAnCCnnnnngGATAnnnnnnnnnnTAnnCCnnnnnGGGAT |
| Binding Sites: | 4yg1_F 4yg1_T 4yg4_F 4yg4_T |
| Publications: | Schumacher MA, Balani P, Min J, Chinnam NB, Hansen S, Vulić M, Lewis K, Brennan RG. HipBA-promoter structures reveal the basis of heritable multidrug tolerance. Nature 524:59-64 (2015). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.