Transcription Factor

						

			
Accessions: Q13360 (JASPAR 2024)

			
Names: ZN177_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q13360
Length: 481
Pfam Domains:     14-54 KRAB box
  163-186 Zinc-finger double domain
  181-196 C2H2-type zinc finger
  276-293 Zinc-finger double domain
  283-306 C2H2-type zinc finger
  284-306 Zinc finger, C2H2 type
  284-306 C2H2-type zinc finger
  298-322 Zinc-finger double domain
  311-334 C2H2-type zinc finger
  312-334 Zinc finger, C2H2 type
  312-334 C2H2-type zinc finger
  326-350 Zinc-finger double domain
  340-362 Zinc finger, C2H2 type
  340-356 C2H2-type zinc finger
  340-362 C2H2-type zinc finger
  354-377 Zinc-finger double domain
  367-390 C2H2-type zinc finger
  368-390 Zinc finger, C2H2 type
  368-390 C2H2-type zinc finger
  382-407 Zinc-finger double domain
  395-418 C2H2-type zinc finger
  396-418 Zinc finger, C2H2 type
  396-418 C2H2-type zinc finger
  413-435 Zinc-finger double domain
  423-442 C2H2-type zinc finger
  424-446 C2H2-type zinc finger
  424-446 Zinc finger, C2H2 type
  439-463 Zinc-finger double domain
  452-474 Zinc finger, C2H2 type
  452-472 C2H2-type zinc finger
  452-474 C2H2-type zinc finger
Sequence: 
(in bold interface residues)		   1 MAAGWLTTWSQNSVTFQEVAVDFSQEEWALLDPAQKNLYKDVMLENFRNLASVGYQLCRH   60
  61 SLISKVDQEQLKTDERGILQGDCADWETQLKPKDTIAMQNIPGGKTSNGINTAENQPGEH  120
 121 SLECNHCGKFRKNTRFICTRYCKGEKCYKYIKYSKVFNHPSTLRSHVSIHIGEKTLEFTD  180
 181 CRKAFNQESSLRKHLRTPTGQKFQEYEQCDMSFSLHSSCSVREQIPTGEKGDECSDYGKI  240
 241 SPLSVHTKTGSVEEGLECNEHEKTFTDPLSLQNCVRTHSGEMPYECSDCGKAFIFQSSLK  300
 301 KHMRSHTGEKPYECDHCGKSFSQSSHLNVHKRTHTGEKPYDCKECGKAFTVPSSLQKHVR  360
 361 THTGEKPYECSDCGKAFIDQSSLKKHTRSHTGEKPYECNQCGKSFSTGSYLIVHKRTHTG  420
 421 EKTYECKECGKAFRNSSCLRVHVRTHTGEKPYKCIQCEKAFSTSTNLIMHKRIHNGQKLH  480
 481 E
Interface Residues: 267, 269, 270, 273, 294, 295, 296, 297, 298, 301, 322, 323, 324, 325, 326, 328, 329, 330, 331, 332, 335, 340, 350, 351, 352, 353, 354, 355, 356, 357, 358, 361, 378, 379, 380, 381, 382, 384, 385, 389, 407, 408, 409, 410, 413, 415, 416, 417, 418, 435, 436, 437, 438, 439, 440, 441, 447, 461, 462, 463, 464, 465, 466, 469, 473
3D-footprint Homologues: 7w1m_H, 2gli_A, 5v3j_F, 1tf3_A, 7n5w_A, 1f2i_J, 6wmi_A, 8ssq_A, 5und_A, 8ssu_A, 1tf6_A, 8gn3_A, 7eyi_G, 6e94_A, 7ysf_A, 3uk3_C, 6jnm_A, 8cuc_F, 7y3l_A, 6u9q_A, 5ei9_F, 5kl3_A, 1g2f_F, 5k5l_F, 6ml4_A, 4x9j_A, 2i13_A, 1llm_D, 5kkq_D, 4m9v_C, 5yel_A, 6a57_A, 2jpa_A, 2kmk_A, 1mey_C, 6blw_A, 8h9h_G, 7y3m_I, 1ubd_C, 2wbs_A, 7txc_E, 5yj3_D, 5k5i_A, 2lt7_A, 2drp_D
Binding Motifs: UN0165.1 bTyGrTCKarsgkmrmAGTCATk
UN0165.2 TyGrTCKarsgkmrmAGTCAT
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.