DNA Binding Motif

						

			
Accessions: ZNF177_2 (HT-SELEX2 May2017), UN0165.1 (JASPAR 2024)

			
Names: ZNF177
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1, JASPAR 2024 2
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: HT-SELEX
Length: 23
Consensus: bTyGrTCKarsgkmrmAGTCATk
Weblogo: 
PSSM: P0      A      C      G      T
01   1279   5258   3654   3518      b
02    213    807    357  13709      T
03   2203   8580   2005   5129      y
04   1368     30  13709    235      G
05   7445      8   6264      2      r
06     13      7     16  13709      T
07      4  13709      5    157      C
08    103    251   9615   4094      K
09   7190   3205   1642   1672      a
10   6782    370   5476   1080      r
11   3241   4247   4307   1913      s
12   1466   1296   7650   3297      g
13    932   1293   7755   3729      k
14   4089   4972   2228   2419      m
15   4691   3217   3903   1899      r
16   4259   5742   2498   1210      m
17  13709    169   2399     99      A
18    318   1490  13709    165      G
19     77    997     23  13709      T
20      6  13709    171      3      C
21  13709      6     16    225      A
22      3     74     25  13709      T
23   2392    677   5064   5576      k
Type: Heterodimer
Binding TFs: ZNF177 (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc finger)
Q13360 (Zinc finger, C2H2 type, KRAB box, Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc finger)
Q13360
			
Publications: Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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