Transcription Factor

						

			
Accessions: HOXC11_full (HumanTF 1.0)

			
Names: Homeobox protein Hox-3H, Homeobox protein Hox-C11, HOXC11, HXC11_HUMAN
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Uniprot: O43248
Notes: Ensembl ID: ENSG00000123388; Full protein sequence; TF family: homeodomain; Clone source: hORFeome
Length: 305
Pfam Domains:    42-178 Protein of unknown function (DUF3528)
  233-289 Homeobox domain
Sequence: 
(in bold interface residues)		   1 MFNSVNLGNFCSPSRKERGADFGERGSCASNLYLPSCTYYMPEFSTVSSFLPQAPSRQIS   60
  61 YPYSAQVPPVREVSYGLEPSGKWHHRNSYSSCYAAADELMHRECLPPSTVTEILMKNEGS  120
 121 YGGHHHPSAPHATPAGFYSSVNKNSVLPQAFDRFFDNAYCGGGDPPAEPPCSGKGEAKGE  180
 181 PEAPPASGLASRAEAGAEAEAEEENTNPSSSGSAHSVAKEPAKGAAPNAPRTRKKRCPYS  240
 241 KFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLSRDRLQYFSG  300
 301 NPLL*
Interface Residues: 233, 234, 235, 236, 274, 275, 277, 278, 281, 282, 284, 285, 286, 289
3D-footprint Homologues: 1ig7_A, 3cmy_A, 8ejp_B, 6a8r_A, 1puf_A, 8pmf_A, 5zfz_A, 1fjl_B, 1zq3_P, 2lkx_A, 3lnq_A, 1nk2_P, 2ld5_A, 5flv_I, 3a01_E, 1b72_A, 5zjt_E, 4cyc_A, 8osb_E, 6m3d_C, 2hdd_A, 2r5y_A, 1jgg_B, 7psx_B, 5jlw_D, 2hos_A, 8eml_B, 6es3_K, 4xrs_G, 1puf_B, 9b8u_A, 7q3o_C, 3rkq_B, 8ik5_C, 1le8_A, 7xrc_C, 1e3o_C, 2xsd_C, 1au7_A, 1o4x_A, 5hod_A, 1le8_B, 1du0_A, 4qtr_D, 1mnm_C, 1k61_B, 6fqq_E
Binding Motifs: HOXC11_full_1 rrTCGTWAAah
HOXC11_full_2 rgymATAAAam
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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