Transcription Factor

						

			
Accessions: 5x6g_B (3D-footprint 20231221)

			
Names: Dwarfin-C, Dwf-C, MAD homolog 5, Mothers against decapentaplegic homolog 5, Mothers against DPP homolog 5, mSmad5, SMAD 5, SMAD family member 5, SMAD5_MOUSE
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P97454
Length: 123
Pfam Domains:    22-122 MH1 domain
Sequence: 
(in bold interface residues)		   1 TSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPGQPSKCVTIPR   60
  61 SLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPYHYKR  120
 121 VES
Interface Residues: 63, 65, 67, 72
3D-footprint Homologues: 6fzs_A, 5od6_A, 6h3r_A, 5nm9_A, 5mey_A
Binding Motifs: 5x6g_AB TGTCTAGACT
Binding Sites: 5x6g_C
5x6g_D
			
Publications: Chai N, Li WX, Wang J, Wang ZX, Yang SM, Wu JW. Structural basis for the Smad5 MH1 domain to recognize different DNA sequences. Nucleic Acids Res 43:9051-64 (2015). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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