DNA Binding Motif

						

			
Accessions: 5x6g_AB (3D-footprint 20231221)

			
Names: Mothers against decapentaplegic homolog 5
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal Structure of SMAD5-MH1/palindromic SBE DNA complex
Length: 10
Consensus: TGTCTAGACT
Weblogo: 
PSSM: P0      A      C      G      T
01      6      6      6     78      T
02      0      0     96      0      G
03      6     12      6     72      T
04      0     96      0      0      C
05      0      0      0     96      T
06     96      0      0      0      A
07      6      6     84      0      G
08     72      6     12      6      A
09      0     96      0      0      C
10      6      6      6     78      T
Type: Heterodimer
Binding TFs: 5x6g_B (MH1 domain)
5x6g_A (MH1 domain)
Binding Sites: 5x6g_C
5x6g_D
			
Publications: Chai N, Li WX, Wang J, Wang ZX, Yang SM, Wu JW. Structural basis for the Smad5 MH1 domain to recognize different DNA sequences. Nucleic Acids Res 43:9051-64 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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