Transcription Factor

Accessions: UP00513A (UniPROBE 20160601)
Names: A.cas Fox, ACA1_126960
Organisms: Acanthamoeba castellanii
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 138
Pfam Domains: 40-104 Fork head domain
Sequence:
(in bold interface residues)
1 HHVEEEEVEEEDYDEVPHPPPRTWVAKAEWALGRLGGRGTLADIYATIEDAFPEEIDGKR 60
61 NWKAAIRSCLSKNEKNKFFKPETMSAAKGDHVWCLAASTPRRATTTTTKRGRPAGRARKP 120
121 PSRTQGRRRSLADERKAV
Interface Residues: 61, 63, 64, 65, 67, 68, 69, 71, 72
3D-footprint Homologues: 7vox_H, 2hdc_A, 7yzb_A, 6ako_C, 7tdx_A, 7yze_A, 6nce_A, 7vou_C, 3g73_A, 7cby_C, 7tdw_A, 2c6y_A, 3qrf_G
Binding Motifs: UP00513A_1 kyywwwkTGYTGCAAtctwrwc
UP00513A_2 akkgyvkcCGCTGCAyhhytsk
Binding Sites: ATGCAGCA
ATGCATCA
GATGCATC
GTGCTGCA
AAGTTGCA
ACGCAACA
ATGCAACA
ATGCTGCA
ATGTTGCG
ATTGCAGC
ATTGTTGC
CCGCTGCA
CGCAACAA
GCAACAAA
GTGCAACA
GTGTTGCA
GTTGCAAC
TGCAACAA
TGCTGCAA
TGTTGCAA
Publications: Nakagawa S, Gisselbrecht SS, Rogers JM, Hartl DL, Bulyk ML. DNA-binding specificity changes in the evolution of forkhead transcription factors. Proc Natl Acad Sci U S A 110:12349-54 (2013). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.